Charles C Horn, PhD Associate Professor, Medicine
Dr. Horn's primary research focus is to determine the biological mechanisms of gut-brain communication. Current interests include studies on the neurobiology of nausea and vomiting, which has applications in the treatment of these symptoms in patients with cancer and gastrointestinal disease. He also has a keen interest in exploring how nausea and vomiting interact with other common clinical symptoms, such as pain, fatigue, and anorexia. His laboratory uses several preclinical models (rodents, musk shrews, and ferrets), computerized behavioral analysis, electrophysiology, and neuroanatomical techniques (immunohistochemistry, radiography, tract tracing). Dr. Horn collaborates with clinicians on translational and patient research. This research program has the long-term goal of developing treatments to decrease symptom burden and improve quality of life for patients.